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David Ros Pardo
(Bilbao, 1994)
CSIC research assistant / Ayudante de investigación CSIC.
PhD student / Estudiante pre-doctoral.
Centro de Biología Molecular Severo Ochoa.
C/ Nicolás Cabrera, 1.
Campus UAM. Cantoblanco, 28049 Madrid. Spain.
Tel: (+34) 91-196-4662 Fax: (+34) 91-196-4420
e-mail: davidrp@cbm.csic.es
URL: http://bioweb.cbm.uam.es / http://www.cbm.csic.es/bioweb
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Academic degrees / Títulos académicos
2016. Graduate in Biology / Graduado en Biología (Universidad del País Vasco/ Euskal Herriko Unibertsitatea, Leioa).
2017. Master in Microbiology and Health / Master en Microbiología (Universidad del País Vasco/ Euskal Herriko Unibertsitatea, Leioa).
2020. Master in Bioinformatics / Máster en Bioinformática (Universidad de Valencia)
Career / Trayectoria profesional.
2020 External practices in the Genetics Department of the IATA-CSIC (Valencia).
2021-date CSIC Research assistant / Ayudante de Investigación CSIC. Molecular Modeling Group - CBM (Madrid).
2021-date PhD student / Estudiante pre-doctoral. Molecular Modeling Group - CBM (Madrid).
Participation in R&D contracts and R&D proyectos / Participación en contratos de I+D y proyectos de I+D.
- 2021-date. Convocatoria Garantía Juvenil Comunidad de Madrid - CSIC.
- 2021-2023. "EPIC Alliance: Alliance for the Exploration of Pipelines for Inhibitors of Carbapenemases". Joint Programming Initiative On Antimicrobial Resistance - JPIAMR Network Plus 2020. (Coord: Dr. Elias Dahdouh, IdiPAZ-Madrid; Principal Inv.: Paulino Gómez-Puertas).
- 2021-2023. "Combating Antibiotic-Resistant Enterobacteriaceae (CARE): structure-based discovery of clinical trial-ready inhibitors". Carlos III Health Institute - Ref: DTS20-00024. (Principal Inv.: Paulino Gómez-Puertas).
- 2022-2025. "New drugs to inhibit Carbapenemases. Discovery of compounds by structural design (DrugCarbapenem)". State Research Agency - Ref: PID2021-126625OB-I00. (Principal Inv.: Paulino Gómez-Puertas).
2022. PATENT
- "MiniACE2 proteins to block SARS-CoV2 infection". 2022. Patent no: NC2022/0005322. Patent in collaboration with the Instituto Distrital de Ciencia, Biotecnología e Innovación en Salud (IDCBIS) of Bogotá, Colombia.
Publications / Publicaciones [ PubMed ] [ ORCID 0000-0002-8934-8585 ]
(A: article/artículo; R: review/revisión; C: book chapter/capítulo de libro; O: other/otros)
2024:
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9(A).-
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Arévalo-Romero, J.A., López-Cantillo, G., Moreno-Jiménez, S., Marcos-Alcalde, I., Ros-Pardo, D., Camacho-Rodríguez, B., *Gómez-Puertas, P. & *Ramírez-Segura, C.A. (*Corresponding authors).
(2024). In-silico design of miniACE2 decoys with in-vitro enhanced neutralization activity against SARS-CoV-2, encompassing Omicron Subvariants.
International Journal of Molecular Sciences 25, 10802.
[PubMed]
[PDF]
[https://doi.org/10.3390/ijms251910802]
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8(A).-
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Ros-Pardo, D., *Gómez-Puertas, P. & Marcos-Alcalde, I. (*Corresponding author).
(2024). STAG2-RAD21 Complex: a Unidirectional DNA Ratchet Mechanism in Loop Extrusion.
International Journal of Biological Macromolecules 276, 133822.
[PubMed]
[PDF]
[https://doi.org/10.1016/j.ijbiomac.2024.133822]
[Supplementary Movie 1]
[Supplementary Movie 2]
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7(A).-
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Furia, F., Levy, A.M.,..., Marcos-Alcalde, I., ..., Ros-Pardo, D., ..., Gómez-Puertas, P., Chung, W.K., Gardella, E. & Tümer, Z.
(2024). The phenotypic and genotypic spectrum of individuals with mono- or biallelic ANK3 variants.
Clinical Genetics 106, 574.
[PubMed]
[PDF]
[https://doi.org/10.1111/cge.14587]
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6(A).-
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Campos-Díaz, A., Morejón-García, P., Monte-Serrano, E., Ros-Pardo, D., Marcos-Alcalde, I., Gómez-Puertas, P. & Lazo, P.A.
(2024). Pathogenic effects of L200P and R387H VRK1 variants on phosphorylation targets and H4K16 acetylation in distal hereditary motor neuropathy.
Journal of Molecular Medicine 102, 801.
[PubMed]
[PDF]
[https://doi.org/10.1007/s00109-024-02442-8]
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5(A).-
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Ros-Pardo, D., *Gómez-Puertas, P. & Marcos-Alcalde, I. (*Corresponding author).
(2024). STAG2: Computational Analysis of Missense Variants Involved in Disease.
International Journal of Molecular Sciences 25, 1280.
[PubMed]
[PDF]
[https://doi.org/10.3390/ijms25021280]
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2023:
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4(A).-
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Colomo, S., Ros-Pardo, D., Oltra, S.S., Gómez-Puertas, P., Sarrió, D. & Moreno-Bueno G.
(2023). Structural and functional insights into GSDMB isoforms complex roles in pathogenesis.
Cell Cycle 22, 2346.
[PubMed]
[PDF]
[https://doi.org/10.1080/15384101.2023.2287933]
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3(A).-
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Oltra, S.S., Colomo, S., Sin, L., Pérez-López, M., Lázaro, S., Molina-Crespo, A., Choi, K-H., Ros-Pardo, D., Martínez, L., Morales, S., González-Páramos, C., Orantes, A., Soriano, M., Hérnandez, A., Lluch, A., Rojo, F., Albanell, J., Gómez-Puertas, P., Ko, J-K., Sarrió, D. & Moreno-Bueno G.
(2023). Distinct GSDMB protein isoforms and protease cleavage processes differentially control pyroptotic cell death and mitochondrial damage in cancer cells.
Cell Death and Differentiation 30, 1366–1381.
[PubMed]
[PDF]
[https://doi.org/10.1038/s41418-023-01143-y]
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2022:
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2(A).-
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Lucía-Campos, C., Valenzuela, I., Latorre-Pellicer, A., Ros-Pardo, D., Gil-Salvador, M., Arnedo, M., Puisac, B., Castells, N., Plaja, A., Tenes, A., Cuscó, I., Trujillano, L., Ramos, F.J., Tizzano, E.F., Gómez-Puertas, P. & Pié, J.
(2022). A novel intragenic duplication in HDAC8 gene underlying a case of Cornelia de Lange syndrome.
Genes 13, 1413.
[PubMed]
[PDF]
[https://doi.org/10.3390/genes13081413]
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1(A).-
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Christensen, M.B., ..., Ros-Pardo, D., ..., Gómez-Puertas, P., Moller, R.S. & Tümer, Z.
(2022). Biallelic variants in ZNF142 lead to a syndromic neurodevelopmental disorder.
Clinical Genetics 102, 98-109.
[PubMed]
[PDF]
[https://doi.org/10.1111/cge.14165]
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Communications presented at meetings / Comunicaciones presentadas en congresos
- 44º Congreso de la Sociedad Española de Bioquímica y Biología Molecular (SEBBM). Málaga, Spain. Sep-2022.
- 2nd Congress "Conexión Cáncer - CSIC". Benidorm, Spain. Jan-2023
- 2nd MOSBRI (Molecular-Scale Biophysics Research Infrastructure) Scientific Conference. Zaragoza, Spain. Jun-2023.
- XII World Congress "Cornelia de Lange Syndrome". Zaragoza, Spain. Nov/Dec-2023.
- The 2024 Annual Congress of the European Association for Cancer Research (EACR). Rotterdam, Netherlands. Jun-2024.
Attendance at courses and conferences / Asistencia a cursos y reuniones
- EMBO Conference and Third International Symposium on the Nitrogen Nutrition of Plants. Montpellier, France. 2016.
- Deep Learning (PyTorch Basics for Machine Learning & Deep Learning with Python and PyTorch). 2020.
- Linux avanzado. Centro de Cálculo Científico de la Universidad Autónoma de Madrid. 2021.
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BIOWEB: MOLECULAR MODELING GROUP
Centro de Biología Molecular Severo Ochoa
(CBM, CSIC-UAM)
http://bioweb.cbm.uam.es |
C/ Nicolás Cabrera, 1. Campus UAM, Cantoblanco
28049 Madrid. Spain
Tel: (+34) 91 196 4662 / 4663
Fax: (+34) 91 196 4420
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