bioweb: molecular modeling group / grupo de modelado molecular

[ http://bioweb.cbm.uam.es ]  [ http://www.cbm.csic.es/bioweb ]

 

David Ros Pardo
(Bilbao, 1994)
CSIC research assistant / Ayudante de investigación CSIC.
PhD student / Estudiante pre-doctoral.

Centro de Biología Molecular Severo Ochoa.
C/ Nicolás Cabrera, 1.
Campus UAM. Cantoblanco, 28049 Madrid. Spain.
Tel: (+34) 91-196-4662   Fax: (+34) 91-196-4420
e-mail: davidrp@cbm.csic.es

URL: http://bioweb.cbm.uam.es / http://www.cbm.csic.es/bioweb

Academic degrees / Títulos académicos
    2016. Graduate in Biology / Graduado en Biología (Universidad del País Vasco/ Euskal Herriko Unibertsitatea, Leioa).
    2017. Master in Microbiology and Health / Master en Microbiología (Universidad del País Vasco/ Euskal Herriko Unibertsitatea, Leioa).
    2020. Master in Bioinformatics / Máster en Bioinformática (Universidad de Valencia)
Career / Trayectoria profesional.
    2020 External practices in the Genetics Department of the IATA-CSIC (Valencia).
    2021-date CSIC Research assistant / Ayudante de Investigación CSIC. Molecular Modeling Group - CBM (Madrid).
    2021-date PhD student / Estudiante pre-doctoral. Molecular Modeling Group - CBM (Madrid).
Participation in R&D contracts and R&D proyectos / Participación en contratos de I+D y proyectos de I+D.
  • 2021-date. Convocatoria Garantía Juvenil Comunidad de Madrid - CSIC.
  • 2021-2023. "EPIC Alliance: Alliance for the Exploration of Pipelines for Inhibitors of Carbapenemases". Joint Programming Initiative On Antimicrobial Resistance - JPIAMR Network Plus 2020. (Coord: Dr. Elias Dahdouh, IdiPAZ-Madrid; Principal Inv.: Paulino Gómez-Puertas).
  • 2021-2023. "Combating Antibiotic-Resistant Enterobacteriaceae (CARE): structure-based discovery of clinical trial-ready inhibitors". Carlos III Health Institute - Ref: DTS20-00024. (Principal Inv.: Paulino Gómez-Puertas).
  • 2022-2025. "New drugs to inhibit Carbapenemases. Discovery of compounds by structural design (DrugCarbapenem)". State Research Agency - Ref: PID2021-126625OB-I00. (Principal Inv.: Paulino Gómez-Puertas).

  • 2022. PATENT
    - "MiniACE2 proteins to block SARS-CoV2 infection". 2022. Patent no: NC2022/0005322. Patent in collaboration with the Instituto Distrital de Ciencia, Biotecnología e Innovación en Salud (IDCBIS) of Bogotá, Colombia.

    Publications / Publicaciones [ PubMed ] [ ORCID 0000-0002-8934-8585 ]
    (A: article/artículo; R: review/revisión; C: book chapter/capítulo de libro; O: other/otros)

     2024:
     
    6(A).-
    Campos-Díaz, A., Morejón-García, P., Monte-Serrano, E., Ros-Pardo, D., Marcos-Alcalde, I., Gómez-Puertas, P. & Lazo, P.A. (2024). Pathogenic effects of L200P and R387H VRK1 variants on phosphorylation targets and H4K16 acetylation in distal hereditary motor neuropathy. Journal of Molecular Medicine. Online ahead of print.  [PubMed]  [PDF]  [https://doi.org/10.1007/s00109-024-02442-8]
    5(A).-
    Ros-Pardo, D., *Gómez-Puertas, P. & Marcos-Alcalde, I. (*Corresponding author). (2024). STAG2: Computational Analysis of Missense Variants Involved in Disease. International Journal of Molecular Sciences 25, 1280.  [PubMed]  [PDF]  [https://doi.org/10.3390/ijms25021280]

     2023:
     
    4(A).-
    Colomo, S., Ros-Pardo, D., Oltra, S.S., Gómez-Puertas, P., Sarrió, D. & Moreno-Bueno G. (2023). Structural and functional insights into GSDMB isoforms complex roles in pathogenesis. Cell Cycle 22, 2346.  [PubMed]  [PDF]  [https://doi.org/10.1080/15384101.2023.2287933]
    3(A).-
    Oltra, S.S., Colomo, S., Sin, L., Pérez-López, M., Lázaro, S., Molina-Crespo, A., Choi, K-H., Ros-Pardo, D., Martínez, L., Morales, S., González-Páramos, C., Orantes, A., Soriano, M., Hérnandez, A., Lluch, A., Rojo, F., Albanell, J., Gómez-Puertas, P., Ko, J-K., Sarrió, D. & Moreno-Bueno G. (2023). Distinct GSDMB protein isoforms and protease cleavage processes differentially control pyroptotic cell death and mitochondrial damage in cancer cells. Cell Death and Differentiation 30, 1366–1381.  [PubMed]  [PDF]  [https://doi.org/10.1038/s41418-023-01143-y]

     2022:
     
    2(A).-
    Lucía-Campos, C., Valenzuela, I., Latorre-Pellicer, A., Ros-Pardo, D., Gil-Salvador, M., Arnedo, M., Puisac, B., Castells, N., Plaja, A., Tenes, A., Cuscó, I., Trujillano, L., Ramos, F.J., Tizzano, E.F., Gómez-Puertas, P. & Pié, J. (2022). A novel intragenic duplication in HDAC8 gene underlying a case of Cornelia de Lange syndrome. Genes 13, 1413.  [PubMed]  [PDF]  [https://doi.org/10.3390/genes13081413]
    1(A).-
    Christensen, M.B., ..., Ros-Pardo, D., ..., Gómez-Puertas, P., Moller, R.S. & Tümer, Z. (2022). Biallelic variants in ZNF142 lead to a syndromic neurodevelopmental disorder. Clinical Genetics 102, 98-109.  [PubMed]  [PDF]  [https://doi.org/10.1111/cge.14165]

    Communications presented at meetings / Comunicaciones presentadas en congresos
    • 44º Congreso de la Sociedad Española de Bioquímica y Biología Molecular (SEBBM). Málaga, Spain. Sep-2022.
    • 2nd Congress "Conexión Cáncer - CSIC". Benidorm, Spain. Jan-2023
    • 2nd MOSBRI (Molecular-Scale Biophysics Research Infrastructure) Scientific Conference. Zaragoza, Spain. Jun-2023.
    • XII World Congress "Cornelia de Lange Syndrome". Zaragoza, Spain. Nov/Dec-2023.
    Attendance at courses and conferences / Asistencia a cursos y reuniones
    • EMBO Conference and Third International Symposium on the Nitrogen Nutrition of Plants. Montpellier, France. 2016.
    • Deep Learning (PyTorch Basics for Machine Learning & Deep Learning with Python and PyTorch). 2020.
    • Linux avanzado. Centro de Cálculo Científico de la Universidad Autónoma de Madrid. 2021.
  • BIOWEB: MOLECULAR MODELING GROUP
    Centro de Biología Molecular Severo Ochoa
    (CBM, CSIC-UAM)
    http://www.cbm.csic.es/bioweb
    C/ Nicolás Cabrera, 1. Campus UAM, Cantoblanco
    28049 Madrid. Spain
    Tel: (+34) 91 196 4662 / 4663
    Fax: (+34) 91 196 4420
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