- Paulino Gómez-Puertas. Research Scientist CSIC / Científico Titular CSIC. (PI)
- Íñigo Marcos Alcalde. Post-doctoral researcher / Investigador postdoctoral.

Research / Investigación:

Computational analysis by molecular dynamics simulation of macromolecular complexes of biomedical interest. Development of a new and efficient drug design system based on computational dynamic simulation of macromolecular structures.

Análisis computacional mediante simulación de dinámica molecular de complejos macromoleculares de interés biomédico. Desarrollo de un nuevo y eficiente sistema de diseño de fármacos basado en simulación computacional dinámica de estructuras macromoleculares.

Latest publications / Últimas publicaciones (PubMed):

Mondaza-Hernandez, J.L., Moura, D.S., Li, Y., Marti, J.L., Gómez-Puertas, P., Nguyen, J.T., Wei, S., Posner, B.A., Meyer, C.A., Bleris, L., Martin-Broto, J. & Hayenga, H. (2025). Identification of BET Inhibitors (BETi) Against Solitary Fibrous Tumor (SFT) Through High-Throughput Screening (HTS). Neoplasia 70, 101244.  [https://doi.org/10.1016/j.neo.2025.101244]

Arnedo, M., Ros-Pardo, D., Puisac, B., Lucia-Campos, C., Gil-Salvador, M., Latorre-Pellicer, A., Marcos-Alcalde, I., Pié, J. & Gómez-Puertas, P. (2025). Ligand–Enzyme Interaction Modeling of Missense Variants Implicated in Mitochondrial HMG-CoA Synthase Deficiency. International Journal of Molecular Sciences 26, 8266.  [https://doi.org/10.3390/ijms26178266]

Moreno-Jiménez, S., Lopez-Cantillo, G., Arévalo-Romero, J.A., Perdomo-Arciniegas, A.M., Moreno-González, A.M., Devia-Mejia, B., Camacho, B.A., Gómez-Puertas, P. & Ramírez-Segura, C.A. (2025). An engineered miniACE2 protein secreted by mesenchymal stromal cells effectively neutralizes multiple SARS-CoV-2 variants in vitro. Molecular Medicine 31, 151.  [https://doi.org/10.1186/s10020-025-01190-w]